Metab Eng. 2008 Jan;10(1):55-68. 13C-metabolic flux analysis of Actinobacillus succinogenes fermentative metabolism at different NaHCO3 and H2 concentrations. McKinlay JB, Vieille C.
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| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | N/A | R02736+R01528 |
| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | N/A | R02736+R01528 |
| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | N/A | R02736+R01528 |
| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | N/A | R02736+R01528 |
| Growth Condition | |
| Strains | Actinobacillus succinogenes 130Z (ATCC 55618) |
| Genotype | Wild type. |
| Culture medium | AM3 medium, AM3 was modified by omitting the 1 g/L NaCl, and adjusting Cys–HCl, Met, and monosodium Glu concentrations to 17, 21, and 240 mg/L. |
| Carbon source | Glucose |
| Growth rate | 0.41/h |
| Case-specific description | 25 mM NaHCO3 under N2,adding 1 M NaCl to maintain identical Na+ concentrations between growth conditions |
| Growth Condition | |
| Strains | Actinobacillus succinogenes 130Z (ATCC 55618) |
| Genotype | Wild type. |
| Culture medium | AM3 medium, AM3 was modified by omitting the 1 g/L NaCl, and adjusting Cys–HCl, Met, and monosodium Glu concentrations to 17, 21, and 240 mg/L. |
| Carbon source | Glucose |
| Growth rate | 0.40/h |
| Case-specific description | 25 mM NaHCO3 under H2,adding 1 M NaCl to maintain identical Na+ concentrations between growth conditions |
| Growth Condition | |
| Strains | Actinobacillus succinogenes 130Z (ATCC 55618) |
| Genotype | Wild type. |
| Culture medium | AM3 medium, AM3 was modified by omitting the 1 g/L NaCl, and adjusting Cys–HCl, Met, and monosodium Glu concentrations to 17, 21, and 240 mg/L. |
| Carbon source | Glucose |
| Growth rate | 0.39/h |
| Case-specific description | 100 mM NaHCO3 under N2 |
| Growth Condition | |
| Strains | Actinobacillus succinogenes 130Z (ATCC 55618) |
| Genotype | Wild type. |
| Culture medium | AM3 medium, AM3 was modified by omitting the 1 g/L NaCl, and adjusting Cys–HCl, Met, and monosodium Glu concentrations to 17, 21, and 240 mg/L. |
| Carbon source | Glucose |
| Growth rate | 0.39/h |
| Case-specific description | 100 mM NaHCO3 under H2 |
| Specific Rate | (mmol g-1 h-1) |
| Glucose | 9.5 |
| Succinate | 5.8 |
| Formate | 6.9 |
| Acetate | 6 |
| Fumarate | 0.03 |
| Ethanol | 2.2 |
| Specific Rate | (mmol g-1 h-1) |
| Glucose | 9.1 |
| Succinate | 5.9 |
| Formate | 7.4 |
| Acetate | 5 |
| Fumarate | 0.018 |
| Ethanol | 2.3 |
| Specific Rate | (mmol g-1 h-1) |
| Glucose | 9.4 |
| Succinate | 7.1 |
| Formate | 4.7 |
| Acetate | 5.6 |
| Fumarate | 0.093 |
| Ethanol | 1.2 |
| Specific Rate | (mmol g-1 h-1) |
| Glucose | 9.4 |
| Succinate | 7.9 |
| Formate | 6.2 |
| Acetate | 4.4 |
| Fumarate | 0.042 |
| Ethanol | 1.4 |