PLoS One. 2008 3(12):e3847. Systems analysis unfolds the relationship between the phosphoketolase pathway and growth in Aspergillus nidulans. Panagiotou G, Andersen MR, Grotkjaer T, et al.
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| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | 113.8 | R02736+R01528 |
| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | 88.8 | R02736+R01528 |
| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | 200 | R02736+R01528 |
| Growth Condition | |
| Strains | Aspergillus nidulans A4 |
| Genotype | Wild type. |
| Culture medium | Minimal medium:10 g/L glucose; 10 mM NaNO3; 0.52 g/L KCl; 0.52g/L MgSO4; 1.52 g/L KH2PO4; 0.0004 g/L CuSO4-5H2O; 0.00004 g/L Na2B2O7-10H2O; 0.0008 g/L FeSO4-7H2O; 0.0008 g/L MnSO4-2H2O; 0.0008 g/L Na2MoO4-2H2O; 0.0008 g/L ZnSO4-7H2O. Arginine (4 mM) was supplemented in the MM used for the selection of transformants. |
| Carbon source | Glucose |
| Growth rate | 0.23/h |
| Case-specific description | Wild type. |
| Growth Condition | |
| Strains | AR1phkGP74 |
| Genotype | Over-expressing phk. |
| Culture medium | Minimal medium:10 g/L glucose; 10 mM NaNO3; 0.52 g/L KCl; 0.52g/L MgSO4; 1.52 g/L KH2PO4; 0.0004 g/L CuSO4-5H2O; 0.00004 g/L Na2B2O7-10H2O; 0.0008 g/L FeSO4-7H2O; 0.0008 g/L MnSO4-2H2O; 0.0008 g/L Na2MoO4-2H2O; 0.0008 g/L ZnSO4-7H2O. Arginine (4 mM) was supplemented in the MM used for the selection of transformants. |
| Carbon source | Glucose |
| Growth rate | 0.23/h |
| Case-specific description | phk. |
| Growth Condition | |
| Strains | AR1phkGP74 |
| Genotype | Over-expressing phk. |
| Culture medium | Minimal medium:10 g/L glucose; 10 mM NaNO3; 0.52 g/L KCl; 0.52g/L MgSO4; 1.52 g/L KH2PO4; 0.0004 g/L CuSO4-5H2O; 0.00004 g/L Na2B2O7-10H2O; 0.0008 g/L FeSO4-7H2O; 0.0008 g/L MnSO4-2H2O; 0.0008 g/L Na2MoO4-2H2O; 0.0008 g/L ZnSO4-7H2O. Arginine (4 mM) was supplemented in the MM used for the selection of transformants. |
| Carbon source | Glucose |
| Growth rate | 0.23/h |
| Case-specific description | phk+IA. Iodo acetate(IA) is a specific and strong inhibitor of glyceraldehyde-3-phosphate dehydrogenase. |
| Specific Rate | (mmol g-1 h-1) |
| Specific Rate | (mmol g-1 h-1) |
| Specific Rate | (mmol g-1 h-1) |