Microbiology. 2005 Jul;151:2209-21. CreA influences the metabolic fluxes of Aspergillus nidulans during growth on glucose and xylose. David H, Krogh AM, Roca C, Akesson M, et al.
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| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | 384.55 | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | 156.2 | R02736+R01528 |
| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | 467.45 | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | 122 | R02736+R01528 |
| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | 533.23 | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | 167.2 | R02736+R01528 |
| Growth Condition | |
| Strains | A. nidulans A187 |
| Genotype | pabaA1 ya2 |
| Culture medium | A defined medium containing trace metal elements and vitamins was used in all cultivations.The medium used had the following composition: 15 g/L (NH4)2SO4, 3 g/L KH2PO4,2 g/L MgSO4-7H2O,2 g/L NaCl, 0.2 g/L CaCl2, 1 mL/L trace element solution, 5 mg/L paminobenzoic acid (PABA) and 1 ml/L antifoam (sb2121).Trace element solution composition (per litre): 14.3 g ZnSO4-H2O, 13.8 g FeSO4-7H2O, 0.5 g NiCl2-6H2O and 2.5 g CuSO4-5H2O. |
| Carbon source | Glucose |
| Growth rate | 0.25/h |
| Case-specific description | The reference strain A. nidulans A187 was grown on glucose. |
| Growth Condition | |
| Strains | A. nidulans creA Delta 4 |
| Genotype | pabaA1 ya2 argB2 |
| Culture medium | A defined medium containing trace metal elements and vitamins was used in all cultivations.The medium used had the following composition: 15 g/L (NH4)2SO4, 3 g/L KH2PO4,2 g/L MgSO4-7H2O,2 g/L NaCl, 0.2 g/L CaCl2, 1 mL/L trace element solution, 5 mg/L paminobenzoic acid (PABA) and 1 ml/L antifoam (sb2121).Trace element solution composition (per litre): 14.3 g ZnSO4-H2O, 13.8 g FeSO4-7H2O, 0.5 g NiCl2-6H2O and 2.5 g CuSO4-5H2O. |
| Carbon source | Glucose |
| Growth rate | 0.11/h |
| Case-specific description | The creA-mutant strain of A. nidulans was grown on glucose. |
| Growth Condition | |
| Strains | A. nidulans creA Delta 4 |
| Genotype | pabaA1 ya2 argB2 |
| Culture medium | A defined medium containing trace metal elements and vitamins was used in all cultivations.The medium used had the following composition: 15 g/L (NH4)2SO4, 3 g/L KH2PO4,2 g/L MgSO4-7H2O,2 g/L NaCl, 0.2 g/L CaCl2, 1 mL/L trace element solution, 5 mg/L paminobenzoic acid (PABA) and 1 ml/L antifoam (sb2121).Trace element solution composition (per litre): 14.3 g ZnSO4-H2O, 13.8 g FeSO4-7H2O, 0.5 g NiCl2-6H2O and 2.5 g CuSO4-5H2O. |
| Carbon source | A mixture of glucose and xylose. |
| Growth rate | 0.11/h |
| Case-specific description | The creA-mutant strain of A. nidulans was grown on a mixture of glucose and xylose. |
| Specific Rate | (mmol g-1 h-1) |
| Specific Rate | (mmol g-1 h-1) |
| Specific Rate | (mmol g-1 h-1) |