Appl Environ Microbiol. 2004 Dec;70(12):7277-87. Metabolic fluxes in Corynebacterium glutamicum during lysine production with sucrose as carbon source. Wittmann C, Kiefer P, Zelder O.
Click on the "GO TO" button to display the flux map.
ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
ATP production rate Minium | 1643.9 | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
NADPH production rate Minium | 222.8 | R02736+R01528 |
Growth Condition | |
Strains | Corynebacterium glutamicum ATCC 21526 |
Genotype | |
Culture medium | Precultures were grown in complex medium containing 5g/L of sucrose.For agar plates,the complex medium was additionally amended with 12g/L of agar.For production of cells as aninoculum for the tracer experiments,a minimal medium with 1mg/L calcium panthotenate HCl was used. |
Carbon source | Sucrose |
Growth rate | |
Case-specific description | In vivo carbon flux distribution in the central metabolism of C.glutamicum ATCC 21526 during lysine production on sucrose. All fluxes are expressed as molar percentages of the mean specific sucrose uptake rate (0.8 mmol/g/h). |
Specific Rate | (mmol g-1 h-1) |
Sucrose | 0.8 |