J Biol Chem. 2004 Mar;279(10):9125-38. Role of transcriptional regulation in controlling fluxes in central carbon metabolism of Saccharomyces cerevisiae. A chemostat culture study. Daran-Lapujade P, Jansen ML, Daran JM, et al.
Click on the "GO TO" button to display the flux map.
| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | 868.25 | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | 689.18 | R02736+R01528 |
| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | 941.11 | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | 65.38 | R02736+R01528 |
| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | 145.16 | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | 0 | R02736+R01528 |
| ATP production rate Maximum | N/A | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R00267+2.5*R08549-R00405+1.5*R00402+2.5*R00342 +2.5*R00214 |
| ATP production rate Minium | 280.33 | -R01786-R04779+2.5*R01061+R01512+R00200+2.5*R00209 +2.5*R08549-R00405+1.5*R00402+2.5*R00342 |
| NADPH production rate Maximum | N/A | R02736+R01528+R00267+R00214 |
| NADPH production rate Minium | 0 | R02736+R01528 |
| Growth Condition | |
| Strains | Saccharomyces cerevisiae CEN.PK113-7D |
| Genotype | Wild type. |
| Culture medium | The defined mineral medium composition was based on that described by Verduyn et al. The carbon source was 256 mmol of carbon/liter. |
| Carbon source | Glucose |
| Growth rate | |
| Case-specific description | Flux distribution in S.cerevisiae grown in chemostat cultivation chemostat cultivation under glucose limitation. |
| Growth Condition | |
| Strains | Saccharomyces cerevisiae CEN.PK113-7D |
| Genotype | Wild type. |
| Culture medium | The defined mineral medium composition was based on that described by Verduyn et al. The carbon source was 256 mmol of carbon/liter. |
| Carbon source | Maltose |
| Growth rate | |
| Case-specific description | Flux distribution in S.cerevisiae grown in chemostat cultivation under maltose limitation |
| Growth Condition | |
| Strains | Saccharomyces cerevisiae CEN.PK113-7D |
| Genotype | Wild type. |
| Culture medium | The defined mineral medium composition was based on that described by Verduyn et al. The carbon source was 256 mmol of carbon/liter. |
| Carbon source | Ethanol |
| Growth rate | |
| Case-specific description | Flux distribution in S.cerevisiae grown in chemostat cultivation under ethanol limitation. |
| Growth Condition | |
| Strains | Saccharomyces cerevisiae CEN.PK113-7D |
| Genotype | Wild type. |
| Culture medium | The defined mineral medium composition was based on that described by Verduyn et al. The carbon source was 256 mmol of carbon/liter. |
| Carbon source | Acetate |
| Growth rate | |
| Case-specific description | Flux distribution in S.cerevisiae grown in chemostat cultivation under acetate limitation. |
| Specific Rate | (mmol g-1 h-1) |
| carbon source | 1.15 |
| O2 | 2.74 |
| CO2 | 2.85 |
| Specific Rate | (mmol g-1 h-1) |
| carbon source | 0.61 |
| O2 | 3.05 |
| CO2 | 3.05 |
| Specific Rate | (mmol g-1 h-1) |
| carbon source | 3.78 |
| O2 | 6.87 |
| CO2 | 3.26 |
| Specific Rate | (mmol g-1 h-1) |
| carbon source | 5.89 |
| O2 | 7.4 |
| CO2 | 7.45 |

